In biotechnology, mixing determines the living conditions of organisms. Achieving the right balance between low shear stress and adequate oxygen transfer, homogeneous nutrient distribution and pH control requires deep process knowledge. We are your reliable partner in scale-up engineering from laboratory-scale to industrial bioreactors.
Mechanimix delivers low-shear mixing solutions for fermentation, cell culture and bioreactor processes in the biotechnology sector. Impeller designs optimized via CFD simulation guarantee sufficient oxygen mass transfer (kLa) and homogeneous nutrient/pH distribution while preserving cell viability.
Each process type requires different mixing parameters, impeller geometry and material selection.
Oxygen transfer and mixing in bacterial, yeast and fungal fermentation. Antibiotic, enzyme and organic acid production.
Minimum shear stress in mammalian cell and hybridoma cultures. Monoclonal antibody and recombinant protein production.
High-viscosity biomass mixing in biogas production. Methane yield enhancement.
Homogeneous light distribution and CO2 transfer in photobioreactors. Biofuel and nutraceutical production.
Optimal mixing for extracellular and intracellular enzyme production. Induction and expression phase management.
Buffer preparation and protein precipitation prior to chromatography. Precise pH and temperature control.
In biotechnology, scale-up is the most critical stage. Achieving the same efficiency at industrial scale as in the laboratory depends on correct scaling of parameters such as geometric similarity, constant tip speed and P/V ratio. We identify scale-up risks in advance through CFD simulation and ensure successful technology transfer.
Let us work together to determine the most suitable mixing solution for your process conditions
Primary mixing for bioreactors and fermenters. NP series ideal for low-shear processes.
Learn More →Zero contamination with magnetic coupling in sterile fermentation. BED-N series for aseptic production.
Learn More →Sterile biological product manufacturing standard
Biological products regulation
Biotechnology automation validation
Hygienic equipment design certification
Aseptic processing standard
For bioprocesses involving solvents
Let our engineering team analyze your biotechnology processes with CFD simulation and design the most efficient mixing solution.
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